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Discovery of G Protein-biased D2 Dopamine Receptor Partial Agonists

Biased ligands (also known as functionally selective ligands) of G protein-coupled receptors are valuable tools for dissecting the roles of G protein-dependent and independent signaling pathways in health and disease. Biased ligands have also been increasingly pursued by the biomedical community as...

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Pubblicato in:J Med Chem
Autori principali: Chen, Xin, McCorvy, John D., Fischer, Matthew G., Butler, Kyle V., Shen, Yudao, Roth, Bryan L., Jin, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148701/
https://ncbi.nlm.nih.gov/pubmed/27805392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01208
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