D(4) Dopamine Receptor High Resolution Structures Enable the Discovery of Selective Agonists

Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Wang, Sheng, Wacker, Daniel, Levit, Anat, Che, Tao, Betz, Robin M., McCorvy, John D., Venkatakrishnan, A. J., Huang, Xi-Ping, Dror, Ron O., Shoichet, Brian K., Roth, Bryan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856174/
https://ncbi.nlm.nih.gov/pubmed/29051383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan5468
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