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D(2) Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine
Functionally selective G protein-coupled receptor ligands are valuable tools for deciphering the roles of downstream signaling pathways that potentially contribute to therapeutic effects versus side effects. Recently, we discovered both G(i/o)-biased and β-arrestin2-biased D(2) receptor agonists bas...
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| Publicado en: | J Med Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509010/ https://ncbi.nlm.nih.gov/pubmed/30964661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b00508 |
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