Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

There is a critical need to improve our understanding of the pathogenesis of melanoma brain metastases (MBMs). Thus, we performed RNA-sequencing (RNA-seq) on 88 resected MBMs and 42 patient-matched extracranial metastases (ECMs); tumors with sufficient tissue also underwent whole exome sequencing, T...

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Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Fischer, Grant M., Jalali, Ali, Kircher, David A., Lee, Won-Chul, McQuade, Jennifer L., Haydu, Lauren E., Joon, Aron Y., Reuben, Alexandre, de Macedo, Mariana P., Carapeto, Fernando C. L., Yang, Chendong, Srivastava, Anuj, Ambati, Chandrashekar R., Sreekumar, Arun, Hudgens, Courtney W., Knighton, Barbara, Deng, Wanleng, Ferguson, Sherise D., Tawbi, Hussein A., Glitza, Isabella C., Gershenwald, Jeffrey E., Gopal, Y. N. Vashisht, Hwu, Patrick, Huse, Jason T., Wargo, Jennifer A., Futreal, P. Andrew, Putluri, Nagireddy, Lazar, Alexander J., DeBerardinis, Ralph J., Marszalek, Joseph R., Zhang, Jianjun, Holmen, Sheri L., Tetzlaff, Michael T., Davies, Michael A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497554/
https://ncbi.nlm.nih.gov/pubmed/30787016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1489
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