Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

There is a critical need to improve our understanding of the pathogenesis of melanoma brain metastases (MBMs). Thus, we performed RNA-sequencing (RNA-seq) on 88 resected MBMs and 42 patient-matched extracranial metastases (ECMs); tumors with sufficient tissue also underwent whole exome sequencing, T...

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Detaylı Bibliyografya
Yayımlandı:Cancer Discov
Asıl Yazarlar: Fischer, Grant M., Jalali, Ali, Kircher, David A., Lee, Won-Chul, McQuade, Jennifer L., Haydu, Lauren E., Joon, Aron Y., Reuben, Alexandre, de Macedo, Mariana P., Carapeto, Fernando C. L., Yang, Chendong, Srivastava, Anuj, Ambati, Chandrashekar R., Sreekumar, Arun, Hudgens, Courtney W., Knighton, Barbara, Deng, Wanleng, Ferguson, Sherise D., Tawbi, Hussein A., Glitza, Isabella C., Gershenwald, Jeffrey E., Gopal, Y. N. Vashisht, Hwu, Patrick, Huse, Jason T., Wargo, Jennifer A., Futreal, P. Andrew, Putluri, Nagireddy, Lazar, Alexander J., DeBerardinis, Ralph J., Marszalek, Joseph R., Zhang, Jianjun, Holmen, Sheri L., Tetzlaff, Michael T., Davies, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497554/
https://ncbi.nlm.nih.gov/pubmed/30787016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1489
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