Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

Human DNA polymerase ι (hPolι) promotes translesion synthesis by inserting nucleotides opposite highly distorting or noninstructional DNA lesions. Here, we provide evidence for the physical interaction of hPolι with proliferating cell nuclear antigen (PCNA), and show that PCNA, together with replica...

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Bibliografiset tiedot
Päätekijät: Haracska, Lajos, Johnson, Robert E., Unk, Ildiko, Phillips, Barbara B., Hurwitz, Jerard, Prakash, Louise, Prakash, Satya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2001
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC64669/
https://ncbi.nlm.nih.gov/pubmed/11724965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261560798
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