Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

Human DNA polymerase ι (hPolι) promotes translesion synthesis by inserting nucleotides opposite highly distorting or noninstructional DNA lesions. Here, we provide evidence for the physical interaction of hPolι with proliferating cell nuclear antigen (PCNA), and show that PCNA, together with replica...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Haracska, Lajos, Johnson, Robert E., Unk, Ildiko, Phillips, Barbara B., Hurwitz, Jerard, Prakash, Louise, Prakash, Satya
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC64669/
https://ncbi.nlm.nih.gov/pubmed/11724965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261560798
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker