Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

Human DNA polymerase ι (hPolι) promotes translesion synthesis by inserting nucleotides opposite highly distorting or noninstructional DNA lesions. Here, we provide evidence for the physical interaction of hPolι with proliferating cell nuclear antigen (PCNA), and show that PCNA, together with replica...

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Detaylı Bibliyografya
Asıl Yazarlar: Haracska, Lajos, Johnson, Robert E., Unk, Ildiko, Phillips, Barbara B., Hurwitz, Jerard, Prakash, Louise, Prakash, Satya
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2001
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC64669/
https://ncbi.nlm.nih.gov/pubmed/11724965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261560798
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