Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA
Human DNA polymerase ι (hPolι) promotes translesion synthesis by inserting nucleotides opposite highly distorting or noninstructional DNA lesions. Here, we provide evidence for the physical interaction of hPolι with proliferating cell nuclear antigen (PCNA), and show that PCNA, together with replica...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64669/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261560798 |
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