Structure‐Activity Relationship of NF023 Derivatives Binding to XIAP‐BIR1

Inhibitors of Apoptosis Proteins (IAPs) are conserved E3‐ligases that ubiquitylate substrates to prevent apoptosis and activate the NF‐kB survival pathway, often deregulated in cancer. IAPs‐mediated regulation of NF‐kB signaling is based on the formation of protein complexes by their type‐I BIR doma...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: Sorrentino, Luca, Cossu, Federica, Milani, Mario, Malkoc, Bilge, Huang, Wen‐Chieh, Tsay, Shwu‐Chen, Ru Hwu, Jih, Mastrangelo, Eloise
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460348/
https://ncbi.nlm.nih.gov/pubmed/31011505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201900059
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados