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Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment
Inhibitor of apoptosis (IAP) proteins are characterized by the presence of the conserved baculoviral IAP repeat (BIR) domain that is involved in protein-protein interactions. IAPs were initially thought to be mainly responsible for caspase inhibition, acting as negative regulators of apoptosis, but...
Tallennettuna:
| Julkaisussa: | Comput Struct Biotechnol J |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Research Network of Computational and Structural Biotechnology
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360406/ https://ncbi.nlm.nih.gov/pubmed/30766663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.01.009 |
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