Structural Insight into Inhibitor of Apoptosis Proteins Recognition by a Potent Divalent Smac-Mimetic

Genetic alterations enhancing cell survival and suppressing apoptosis are hallmarks of cancer that significantly reduce the efficacy of chemotherapy or radiotherapy. The Inhibitor of Apoptosis Protein (IAP) family hosts conserved proteins in the apoptotic pathway whose over-expression, frequently fo...

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Dades bibliogràfiques
Autors principals: Cossu, Federica, Milani, Mario, Vachette, Patrice, Malvezzi, Francesca, Grassi, Serena, Lecis, Daniele, Delia, Domenico, Drago, Carmelo, Seneci, Pierfausto, Bolognesi, Martino, Mastrangelo, Eloise
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499469/
https://ncbi.nlm.nih.gov/pubmed/23166698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049527
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