Structural Insight into Inhibitor of Apoptosis Proteins Recognition by a Potent Divalent Smac-Mimetic

Genetic alterations enhancing cell survival and suppressing apoptosis are hallmarks of cancer that significantly reduce the efficacy of chemotherapy or radiotherapy. The Inhibitor of Apoptosis Protein (IAP) family hosts conserved proteins in the apoptotic pathway whose over-expression, frequently fo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cossu, Federica, Milani, Mario, Vachette, Patrice, Malvezzi, Francesca, Grassi, Serena, Lecis, Daniele, Delia, Domenico, Drago, Carmelo, Seneci, Pierfausto, Bolognesi, Martino, Mastrangelo, Eloise
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499469/
https://ncbi.nlm.nih.gov/pubmed/23166698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049527
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