XIAP induces NF-κB activation via the BIR1/TAB1 interaction and BIR1 dimerization

In addition to caspase inhibition, X-linked inhibitor of apoptosis (XIAP) induces NF-κB and MAP kinase activation during TGFβ and BMP receptor signaling and upon overexpression. Here we show that the BIR1 domain of XIAP, which has no previously ascribed function, directly interacts with TAB1 to indu...

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Huvudupphovsmän: Lu, Miao, Lin, Su-Chang, Huang, Yihua, Kang, Young Jun, Rich, Rebecca, Lo, Yu-Chih, Myszka, David, Han, Jiahuai, Wu, Hao
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991276/
https://ncbi.nlm.nih.gov/pubmed/17560374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.05.006
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