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XIAP induces NF-κB activation via the BIR1/TAB1 interaction and BIR1 dimerization

In addition to caspase inhibition, X-linked inhibitor of apoptosis (XIAP) induces NF-κB and MAP kinase activation during TGFβ and BMP receptor signaling and upon overexpression. Here we show that the BIR1 domain of XIAP, which has no previously ascribed function, directly interacts with TAB1 to indu...

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Detalhes bibliográficos
Main Authors: Lu, Miao, Lin, Su-Chang, Huang, Yihua, Kang, Young Jun, Rich, Rebecca, Lo, Yu-Chih, Myszka, David, Han, Jiahuai, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991276/
https://ncbi.nlm.nih.gov/pubmed/17560374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.05.006
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