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XIAP induces NF-κB activation via the BIR1/TAB1 interaction and BIR1 dimerization
In addition to caspase inhibition, X-linked inhibitor of apoptosis (XIAP) induces NF-κB and MAP kinase activation during TGFβ and BMP receptor signaling and upon overexpression. Here we show that the BIR1 domain of XIAP, which has no previously ascribed function, directly interacts with TAB1 to indu...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1991276/ https://ncbi.nlm.nih.gov/pubmed/17560374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.05.006 |
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