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Ski drives an acute increase in MMP‐9 gene expression and release in primary cardiac myofibroblasts

Many etiologies of heart disease are characterized by expansion and remodeling of the cardiac extracellular matrix (ECM or matrix) which results in cardiac fibrosis. Cardiac fibrosis is mediated in cardiac fibroblasts by TGF‐β (1)/R‐Smad2/3 signaling. Matrix component proteins are synthesized by act...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Landry, Natalie, Kavosh, Morvarid S., Filomeno, Krista L., Rattan, Sunil G., Czubryt, Michael P., Dixon, Ian M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429976/
https://ncbi.nlm.nih.gov/pubmed/30488595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13897
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