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Ski drives an acute increase in MMP‐9 gene expression and release in primary cardiac myofibroblasts
Many etiologies of heart disease are characterized by expansion and remodeling of the cardiac extracellular matrix (ECM or matrix) which results in cardiac fibrosis. Cardiac fibrosis is mediated in cardiac fibroblasts by TGF‐β (1)/R‐Smad2/3 signaling. Matrix component proteins are synthesized by act...
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| Veröffentlicht in: | Physiol Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429976/ https://ncbi.nlm.nih.gov/pubmed/30488595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13897 |
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