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Cardiac Fibroblast to Myofibroblast Phenotype Conversion—An Unexploited Therapeutic Target

Fibrosis occurs when the synthesis of extracellular matrix outpaces its degradation, and over time can negatively impact tissue and organ function. In the case of cardiac fibrosis, contraction and relaxation of the heart can be impaired to the point of precipitating heart failure, while at the same...

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Bibliografiske detaljer
Udgivet i:J Cardiovasc Dev Dis
Hovedforfatter: Czubryt, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787657/
https://ncbi.nlm.nih.gov/pubmed/31426390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcdd6030028
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