The transcription factor scleraxis is a critical regulator of cardiac fibroblast phenotype

BACKGROUND: Resident fibroblasts synthesize the cardiac extracellular matrix, and can undergo phenotype conversion to myofibroblasts to augment matrix production, impairing function and contributing to organ failure. A significant gap in our understanding of the transcriptional regulation of these p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Biol
Prif Awduron: Bagchi, Rushita A., Roche, Patricia, Aroutiounova, Nina, Espira, Leon, Abrenica, Bernard, Schweitzer, Ronen, Czubryt, Michael P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794909/
https://ncbi.nlm.nih.gov/pubmed/26988708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0243-8
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