Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts

The incidence of heart failure with concomitant cardiac fibrosis is very high in developed countries. Fibroblast activation in heart is causal to cardiac fibrosis as they convert to hypersynthetic cardiac myofibroblasts. There is no known treatment for cardiac fibrosis. Myofibroblasts contribute to...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Gupta, Shivika S., Zeglinski, Matthew R., Rattan, Sunil G., Landry, Natalie M., Ghavami, Saeid, Wigle, Jeffrey T., Klonisch, Thomas, Halayko, Andrew J., Dixon, Ian M.C.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346657/
https://ncbi.nlm.nih.gov/pubmed/27705938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12392
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