Ski drives an acute increase in MMP‐9 gene expression and release in primary cardiac myofibroblasts

Many etiologies of heart disease are characterized by expansion and remodeling of the cardiac extracellular matrix (ECM or matrix) which results in cardiac fibrosis. Cardiac fibrosis is mediated in cardiac fibroblasts by TGF‐β (1)/R‐Smad2/3 signaling. Matrix component proteins are synthesized by act...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Physiol Rep
Main Authors: Landry, Natalie, Kavosh, Morvarid S., Filomeno, Krista L., Rattan, Sunil G., Czubryt, Michael P., Dixon, Ian M. C.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429976/
https://ncbi.nlm.nih.gov/pubmed/30488595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13897
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