Ski drives an acute increase in MMP‐9 gene expression and release in primary cardiac myofibroblasts

Many etiologies of heart disease are characterized by expansion and remodeling of the cardiac extracellular matrix (ECM or matrix) which results in cardiac fibrosis. Cardiac fibrosis is mediated in cardiac fibroblasts by TGF‐β (1)/R‐Smad2/3 signaling. Matrix component proteins are synthesized by act...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Autores principales: Landry, Natalie, Kavosh, Morvarid S., Filomeno, Krista L., Rattan, Sunil G., Czubryt, Michael P., Dixon, Ian M. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429976/
https://ncbi.nlm.nih.gov/pubmed/30488595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13897
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