Ski drives an acute increase in MMP‐9 gene expression and release in primary cardiac myofibroblasts

Many etiologies of heart disease are characterized by expansion and remodeling of the cardiac extracellular matrix (ECM or matrix) which results in cardiac fibrosis. Cardiac fibrosis is mediated in cardiac fibroblasts by TGF‐β (1)/R‐Smad2/3 signaling. Matrix component proteins are synthesized by act...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Landry, Natalie, Kavosh, Morvarid S., Filomeno, Krista L., Rattan, Sunil G., Czubryt, Michael P., Dixon, Ian M. C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429976/
https://ncbi.nlm.nih.gov/pubmed/30488595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13897
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