Colorectal carcinomas containing hypermethylated MLH1 promoter and wild type BRAF/KRAS are enriched for targetable kinase fusions

Lignende værker

• Reliable Clinical MLH1 Promoter Hypermethylation Assessment Using a High-Throughput Genome-Wide Methylation Array Platform
  af: Benhamida, Jamal K., et al.
  Udgivet: (2020)
• Retained Mismatch Repair Protein Expression Occurs in Approximately 6% of Microsatellite Instability-High Cancers and is Associated with Missense Mutations in Mismatch Repair Genes.
  af: Hechtman, Jaclyn F., et al.
  Udgivet: (2019)
• Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and somatic MSH2 mutations
  af: Wang, Tao, et al.
  Udgivet: (2018)
• Majority of B2M-Mutant and -Deficient Colorectal Carcinomas Achieve Clinical Benefit From Immune Checkpoint Inhibitor Therapy and Are Microsatellite Instability-High
  af: Middha, Sumit, et al.
  Udgivet: (2019)
• Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF
  af: Hechtman, Jaclyn F., et al.
  Udgivet: (2015)