Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity

Cellular life requires the activation of the ADP-ribosylation factors (ARFs) by Golgi brefeldin A-resistant factor 1 (GBF1), a guanine nucleotide exchange factor (GEF) with a highly conserved catalytic Sec7 domain (Sec7d). In addition to the Sec7d, GBF1 contains other conserved domains whose functio...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Pocognoni, Cristian A., Viktorova, Ekaterina G., Wright, John, Meissner, Justyna M., Sager, Garrett, Lee, Eunjoo, Belov, George A., Sztul, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338321/
https://ncbi.nlm.nih.gov/pubmed/29443553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00221.2017
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