Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity

Cellular life requires the activation of the ADP-ribosylation factors (ARFs) by Golgi brefeldin A-resistant factor 1 (GBF1), a guanine nucleotide exchange factor (GEF) with a highly conserved catalytic Sec7 domain (Sec7d). In addition to the Sec7d, GBF1 contains other conserved domains whose functio...

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Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Pocognoni, Cristian A., Viktorova, Ekaterina G., Wright, John, Meissner, Justyna M., Sager, Garrett, Lee, Eunjoo, Belov, George A., Sztul, Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338321/
https://ncbi.nlm.nih.gov/pubmed/29443553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00221.2017
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