Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation

Members of the large Sec7 domain-containing Arf guanine nucleotide exchange factor (GEF) family have been shown to dimerize through their NH(2)-terminal dimerization and cyclophilin binding (DCB) and homology upstream of Sec7 (HUS) domains. However, the importance of dimerization in GEF localization...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Bhatt, Jay M., Viktorova, Ekaterina G., Busby, Theodore, Wyrozumska, Paulina, Newman, Laura E., Lin, Helen, Lee, Eunjoo, Wright, John, Belov, George A., Kahn, Richard A., Sztul, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796281/
https://ncbi.nlm.nih.gov/pubmed/26718629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00185.2015
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