Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity

Cellular life requires the activation of the ADP-ribosylation factors (ARFs) by Golgi brefeldin A-resistant factor 1 (GBF1), a guanine nucleotide exchange factor (GEF) with a highly conserved catalytic Sec7 domain (Sec7d). In addition to the Sec7d, GBF1 contains other conserved domains whose functio...

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發表在:Am J Physiol Cell Physiol
Main Authors: Pocognoni, Cristian A., Viktorova, Ekaterina G., Wright, John, Meissner, Justyna M., Sager, Garrett, Lee, Eunjoo, Belov, George A., Sztul, Elizabeth
格式: Artigo
語言:Inglês
出版: American Physiological Society 2018
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338321/
https://ncbi.nlm.nih.gov/pubmed/29443553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00221.2017
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