Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity

Cellular life requires the activation of the ADP-ribosylation factors (ARFs) by Golgi brefeldin A-resistant factor 1 (GBF1), a guanine nucleotide exchange factor (GEF) with a highly conserved catalytic Sec7 domain (Sec7d). In addition to the Sec7d, GBF1 contains other conserved domains whose functio...

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Publicado en:Am J Physiol Cell Physiol
Autores principales: Pocognoni, Cristian A., Viktorova, Ekaterina G., Wright, John, Meissner, Justyna M., Sager, Garrett, Lee, Eunjoo, Belov, George A., Sztul, Elizabeth
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338321/
https://ncbi.nlm.nih.gov/pubmed/29443553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00221.2017
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