Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity

Cellular life requires the activation of the ADP-ribosylation factors (ARFs) by Golgi brefeldin A-resistant factor 1 (GBF1), a guanine nucleotide exchange factor (GEF) with a highly conserved catalytic Sec7 domain (Sec7d). In addition to the Sec7d, GBF1 contains other conserved domains whose functio...

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Bibliografske podrobnosti
izdano v:Am J Physiol Cell Physiol
Main Authors: Pocognoni, Cristian A., Viktorova, Ekaterina G., Wright, John, Meissner, Justyna M., Sager, Garrett, Lee, Eunjoo, Belov, George A., Sztul, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338321/
https://ncbi.nlm.nih.gov/pubmed/29443553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00221.2017
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