The ARF guanine nucleotide exchange factor GBF1 is targeted to Golgi membranes through a PIP-binding domain

ADP-ribosylation factors (ARF) GTPases are activated by guanine nucleotide exchange factors (GEFs) to support cellular homeostasis. Key to understanding spatio-temporal regulation of ARF signaling is the mechanism of GEF recruitment to membranes. Small GEFs are recruited through phosphoinositide (PI...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Meissner, Justyna M., Bhatt, Jay M., Lee, Eunjoo, Styers, Melanie L., Ivanova, Anna A., Kahn, Richard A., Sztul, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2018
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826047/
https://ncbi.nlm.nih.gov/pubmed/29361542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.210245
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