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A Redundant Mechanism of Recruitment Underlies the Remarkable Plasticity of the Requirement of Poliovirus Replication for the Cellular ArfGEF GBF1

The replication of many positive-strand RNA viruses [(+)RNA viruses] depends on the cellular protein GBF1, but its role in the replication process is not clear. In uninfected cells, GBF1 activates small GTPases of the Arf family and coordinates multiple steps of membrane metabolism, including functi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Viktorova, Ekaterina G., Gabaglio, Samuel, Meissner, Justyna M., Lee, Eunjoo, Moghimi, Seyedehmahsa, Sztul, Elizabeth, Belov, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803275/
https://ncbi.nlm.nih.gov/pubmed/31375590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00856-19
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