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Poliovirus replication requires the N‐terminus but not the catalytic Sec7 domain of ArfGEF GBF1

Viruses are intracellular parasites whose reproduction relies on factors provided by the host. The cellular protein GBF1 is critical for poliovirus replication. Here we show that the contribution of GBF1 to virus replication is different from its known activities in uninfected cells. Normally GBF1 a...

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Détails bibliographiques
Auteurs principaux: Belov, George A., Kovtunovych, Gennadiy, Jackson, Catherine L., Ehrenfeld, Ellie
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945620/
https://ncbi.nlm.nih.gov/pubmed/20497182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01482.x
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