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A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
Excitatory neurons are preferentially impaired in early Alzheimer’s disease but the pathways contributing to their relative vulnerability remain largely unknown. Here we report that pathological tau accumulation takes place predominantly in excitatory neurons compared to inhibitory neurons, not only...
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| 出版年: | Nat Neurosci |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6330709/ https://ncbi.nlm.nih.gov/pubmed/30559469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0298-7 |
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