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Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age dependent manner

During aging, decreased efficiency of nuclear factor E2-related factor 2 (Nrf2) activation and autophagic processes in the brain may be a contributing factor in the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease. Therefore, we analyzed the expression of BAG3, a co-chaperone t...

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Tang, Maoping, Ji, Changyi, Pallo, Susanne, Rahman, Irfan, Johnson, Gail V.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801049/
https://ncbi.nlm.nih.gov/pubmed/29304346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.12.001
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