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New application of β-galactosidase complementation to monitor tau self-association

Neurofibrillary tangles composed of hyperphosphorylated and aberrantly cleaved microtubule-associated protein tau are a major neuropathological hallmark of Alzheimer's disease. Recent studies suggest that the predominant neurotoxic effect of pathologically processed tau is mediated by intermedi...

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Detalhes bibliográficos
Main Authors: Ding, Huiping, Johnson, Gail V.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664461/
https://ncbi.nlm.nih.gov/pubmed/18498442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05496.x
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