Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4

Cancer cells rely on dysregulated gene expression. This establishes specific transcriptional addictions that may be therapeutically exploited. Yet, the mechanisms ultimately responsible for these addictions are poorly understood. Here we investigated the transcriptional dependencies of transformed c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nat Med
Hauptverfasser: Zanconato, Francesca, Battilana, Giusy, Forcato, Mattia, Filippi, Letizia, Azzolin, Luca, Manfrin, Andrea, Quaranta, Erika, Di Biagio, Daniele, Sigismondo, Gianluca, Guzzardo, Vincenza, Lejeune, Pascale, Haendler, Bernard, Krijgsveld, Jeroen, Fassan, Matteo, Bicciato, Silvio, Cordenonsi, Michelangelo, Piccolo, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181206/
https://ncbi.nlm.nih.gov/pubmed/30224758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0158-8
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge