Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4

Cancer cells rely on dysregulated gene expression. This establishes specific transcriptional addictions that may be therapeutically exploited. Yet, the mechanisms ultimately responsible for these addictions are poorly understood. Here we investigated the transcriptional dependencies of transformed c...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Med
Hoofdauteurs: Zanconato, Francesca, Battilana, Giusy, Forcato, Mattia, Filippi, Letizia, Azzolin, Luca, Manfrin, Andrea, Quaranta, Erika, Di Biagio, Daniele, Sigismondo, Gianluca, Guzzardo, Vincenza, Lejeune, Pascale, Haendler, Bernard, Krijgsveld, Jeroen, Fassan, Matteo, Bicciato, Silvio, Cordenonsi, Michelangelo, Piccolo, Stefano
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181206/
https://ncbi.nlm.nih.gov/pubmed/30224758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0158-8
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items