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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
YAP/TAZ are nuclear effectors of the Hippo pathway regulating organ growth and tumorigenesis. Yet, their working as transcriptional regulators remains underinvestigated. By ChIP-seq analyses in breast cancer cells, we discovered that the YAP/TAZ transcriptional response is pervasively mediated by a...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6186417/ https://ncbi.nlm.nih.gov/pubmed/26258633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3216 |
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