Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

YAP/TAZ are nuclear effectors of the Hippo pathway regulating organ growth and tumorigenesis. Yet, their working as transcriptional regulators remains underinvestigated. By ChIP-seq analyses in breast cancer cells, we discovered that the YAP/TAZ transcriptional response is pervasively mediated by a...

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Detaylı Bibliyografya
Yayımlandı:Nat Cell Biol
Asıl Yazarlar: Zanconato, Francesca, Forcato, Mattia, Battilana, Giusy, Azzolin, Luca, Quaranta, Erika, Bodega, Beatrice, Rosato, Antonio, Bicciato, Silvio, Cordenonsi, Michelangelo, Piccolo, Stefano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186417/
https://ncbi.nlm.nih.gov/pubmed/26258633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3216
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