SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement

The entry of human immunodeficiency virus into host cells is mediated by the envelope glycoprotein (Env) trimeric spike, which consists of three exterior gp120 subunits and three transmembrane gp41 subunits. The trimeric Env undergoes extensive conformational rearrangement upon interaction with the...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Alsahafi, Nirmin, Anand, Sai Priya, Castillo-Menendez, Luis, Verly, Myriam Maude, Medjahed, Halima, Prévost, Jérémie, Herschhorn, Alon, Richard, Jonathan, Schön, Arne, Melillo, Bruno, Freire, Ernesto, Smith, Amos B., Sodroski, Joseph, Finzi, Andrés
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146791/
https://ncbi.nlm.nih.gov/pubmed/30021898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01080-18
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