Grafting Neural Stem and Progenitor Cells Into the Hippocampus of Juvenile, Irradiated Mice Normalizes Behavior Deficits

The pool of neural stem and progenitor cells (NSPCs) in the dentate gyrus of the hippocampus is reduced by ionizing radiation. This explains, at least partly, the learning deficits observed in patients after radiotherapy, particularly in pediatric cases. An 8 Gy single irradiation dose was delivered...

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Опубликовано в: :Front Neurol
Главные авторы: Sato, Yoshiaki, Shinjyo, Noriko, Sato, Machiko, Nilsson, Marie K. L., Osato, Kazuhiro, Zhu, Changlian, Pekna, Marcela, Kuhn, Hans G., Blomgren, Klas
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Neurology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141740/
https://ncbi.nlm.nih.gov/pubmed/30254600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00715
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