Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia

BACKGROUND: A considerable proportion of all newly generated cells in the hippocampus will die before becoming fully differentiated, both under normal and pathological circumstances. The caspase-independent apoptosis-inducing factor (AIF) has not been investigated previously in this context. RESULTS...

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Main Authors: Sun, Yanyan, Zhang, Yu, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464153/
https://ncbi.nlm.nih.gov/pubmed/22534064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-17
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