Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia

Mitochondria contribute to neonatal hypoxic-ischemic brain injury by releasing potentially toxic proteins into the cytosol. CHCHD4 is a mitochondrial intermembrane space protein that plays a major role in the import of intermembrane proteins and physically interacts with apoptosis-inducing factor (A...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sun, Yanyan, Li, Tao, Xie, Cuicui, Xu, Yiran, Zhou, Kai, Rodriguez, Juan, Han, Wei, Wang, Xiaoyang, Kroemer, Guido, Modjtahedi, Nazanine, Blomgren, Klas, Zhu, Changlian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520716/
https://ncbi.nlm.nih.gov/pubmed/28492551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.196
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