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Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice

The purpose of this study was to evaluate the effect of dichloroacetate (DCA) treatment for brain injury in neonatal mice after hypoxia ischemia (HI) and the possible molecular mechanisms behind this effect. Postnatal day 9 male mouse pups were subjected to unilateral HI, DCA was injected intraperit...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Yanyan, Li, Tao, Xie, Cuicui, Zhang, Yaodong, Zhou, Kai, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077971/
https://ncbi.nlm.nih.gov/pubmed/27153546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9150
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