Selective Neural Deletion of the Atg7 Gene Reduces Irradiation-Induced Cerebellar White Matter Injury in the Juvenile Mouse Brain by Ameliorating Oligodendrocyte Progenitor Cell Loss

Radiotherapy is an effective tool for treating brain tumors, but irradiation-induced toxicity to the normal brain tissue remains a major problem. Here, we investigated if selective neural autophagy related gene 7 (Atg7) deletion has a persistent effect on irradiation-induced juvenile mouse brain inj...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Wang, Yafeng, Zhou, Kai, Li, Tao, Xu, Yiran, Xie, Cuicui, Sun, Yanyan, Rodriguez, Juan, Zhang, Shan, Song, Juan, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554477/
https://ncbi.nlm.nih.gov/pubmed/31213984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00241
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