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Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain

Cranial radiotherapy in children typically causes delayed and progressive cognitive dysfunction and there is no effective preventive strategy for radiation-induced cognitive impairments. Here we show that lithium treatment reduced irradiation-induced progenitor cell death in the subgranular zone of...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhou, Kai, Xie, Cuicui, Wickström, Malin, Dolga, Amalia M., Zhang, Yaodong, Li, Tao, Xu, Yiran, Culmsee, Carsten, Kogner, Per, Zhu, Changlian, Blomgren, Klas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470955/
https://ncbi.nlm.nih.gov/pubmed/28415806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16292
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