Lithium increases proliferation of hippocampal neural stem/progenitor cells and rescues irradiation-induced cell cycle arrest in vitro

Radiotherapy in children causes debilitating cognitive decline, partly linked to impaired neurogenesis. Irradiation targets primarily cancer cells but also endogenous neural stem/progenitor cells (NSPCs) leading to cell death or cell cycle arrest. Here we evaluated the effects of lithium on prolifer...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zanni, Giulia, Di Martino, Elena, Omelyanenko, Anna, Andäng, Michael, Delle, Ulla, Elmroth, Kecke, Blomgren, Klas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research paper: Autophagy and Cell Death
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741917/
https://ncbi.nlm.nih.gov/pubmed/26397227
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