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C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning

Radiotherapy in the treatment of pediatric brain tumors is often associated with debilitating late-appearing adverse effects, such as intellectual impairment. Areas in the brain harboring stem cells are particularly sensitive to irradiation (IR) and loss of these cells may contribute to cognitive de...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Kalm, Marie, Andreasson, Ulf, Björk-Eriksson, Thomas, Zetterberg, Henrik, Pekny, Milos, Blennow, Kaj, Pekna, Marcela, Blomgren, Klas
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991390/
https://ncbi.nlm.nih.gov/pubmed/27029069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8400
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