Inhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain

Radiotherapy is an effective tool in the treatment of malignant brain tumors. However, damage to brain stem and progenitor cells constitutes a major problem and is associated with long-term side effects. Autophagy has been shown to be involved in cell death, and the purpose of this study was to eval...

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Vydáno v:Cell Death Dis
Hlavní autoři: Wang, Yafeng, Zhou, Kai, Li, Tao, Xu, Yiran, Xie, Cuicui, Sun, Yanyan, Zhang, Yaodong, Rodriguez, Juan, Blomgren, Klas, Zhu, Changlian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386526/
https://ncbi.nlm.nih.gov/pubmed/28333139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.120
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