Radiation induces progenitor cell death, microglia activation, and blood-brain barrier damage in the juvenile rat cerebellum

Posterior fossa tumors are the most common childhood intracranial tumors, and radiotherapy is one of the most effective treatments. However, irradiation induces long-term adverse effects that can have significant negative impacts on the patient’s quality of life. The purpose of this study was to cha...

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Udgivet i:Sci Rep
Main Authors: Zhou, Kai, Boström, Martina, Ek, C. Joakim, Li, Tao, Xie, Cuicui, Xu, Yiran, Sun, Yanyan, Blomgren, Klas, Zhu, Changlian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382769/
https://ncbi.nlm.nih.gov/pubmed/28382975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46181
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