Grafting Neural Stem and Progenitor Cells Into the Hippocampus of Juvenile, Irradiated Mice Normalizes Behavior Deficits

The pool of neural stem and progenitor cells (NSPCs) in the dentate gyrus of the hippocampus is reduced by ionizing radiation. This explains, at least partly, the learning deficits observed in patients after radiotherapy, particularly in pediatric cases. An 8 Gy single irradiation dose was delivered...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Neurol
Auteurs principaux: Sato, Yoshiaki, Shinjyo, Noriko, Sato, Machiko, Nilsson, Marie K. L., Osato, Kazuhiro, Zhu, Changlian, Pekna, Marcela, Kuhn, Hans G., Blomgren, Klas
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Neurology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141740/
https://ncbi.nlm.nih.gov/pubmed/30254600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00715
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