Grafting Neural Stem and Progenitor Cells Into the Hippocampus of Juvenile, Irradiated Mice Normalizes Behavior Deficits

The pool of neural stem and progenitor cells (NSPCs) in the dentate gyrus of the hippocampus is reduced by ionizing radiation. This explains, at least partly, the learning deficits observed in patients after radiotherapy, particularly in pediatric cases. An 8 Gy single irradiation dose was delivered...

Full description

Saved in:
Bibliographic Details
Published in:Front Neurol
Main Authors: Sato, Yoshiaki, Shinjyo, Noriko, Sato, Machiko, Nilsson, Marie K. L., Osato, Kazuhiro, Zhu, Changlian, Pekna, Marcela, Kuhn, Hans G., Blomgren, Klas
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neurology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141740/
https://ncbi.nlm.nih.gov/pubmed/30254600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00715
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items