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Carbamylated Erythropoietin Decreased Proliferation and Neurogenesis in the Subventricular Zone, but Not the Dentate Gyrus, After Irradiation to the Developing Rat Brain

Cranial radiotherapy for pediatric brain tumors causes progressive, debilitating late effects, including cognitive decline. Erythropoietin (EPO) has been shown to be neuroprotective and to promote neuroregeneration. Carbamylated erythropoietin (CEPO) retains the protective properties of EPO but is n...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Osato, Kazuhiro, Sato, Yoshiaki, Osato, Akari, Sato, Machiko, Zhu, Changlian, Leist, Marcel, Kuhn, Hans G., Blomgren, Klas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143677/
https://ncbi.nlm.nih.gov/pubmed/30258396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00738
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