Carbamylated Erythropoietin Decreased Proliferation and Neurogenesis in the Subventricular Zone, but Not the Dentate Gyrus, After Irradiation to the Developing Rat Brain

Cranial radiotherapy for pediatric brain tumors causes progressive, debilitating late effects, including cognitive decline. Erythropoietin (EPO) has been shown to be neuroprotective and to promote neuroregeneration. Carbamylated erythropoietin (CEPO) retains the protective properties of EPO but is n...

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Vydáno v:Front Neurol
Hlavní autoři: Osato, Kazuhiro, Sato, Yoshiaki, Osato, Akari, Sato, Machiko, Zhu, Changlian, Leist, Marcel, Kuhn, Hans G., Blomgren, Klas
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143677/
https://ncbi.nlm.nih.gov/pubmed/30258396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00738
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