Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain

Cranial radiotherapy in children typically causes delayed and progressive cognitive dysfunction and there is no effective preventive strategy for radiation-induced cognitive impairments. Here we show that lithium treatment reduced irradiation-induced progenitor cell death in the subgranular zone of...

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Publicado en:Oncotarget
Autores principales: Zhou, Kai, Xie, Cuicui, Wickström, Malin, Dolga, Amalia M., Zhang, Yaodong, Li, Tao, Xu, Yiran, Culmsee, Carsten, Kogner, Per, Zhu, Changlian, Blomgren, Klas
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Autophagy and Cell Death
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470955/
https://ncbi.nlm.nih.gov/pubmed/28415806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16292
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